Khyber Pakhtunkhwa won the 2021 edition of the Pakistan National T20 Cup after defeating Central Punjab by seven wickets. They chased down 149 with three overs to spare.
Most Runs
Sahibzada Farhan made 26 in 28 balls to finish the season with 447 runs. Iftikhar Ahmed, his teammate, is the only other player to cross the 400-run mark. He smashed 45 off just 19 deliveries, with six fours and two sixes, to finish the season with 409 to his name. Central Punjab's Ahmed Shehzad top-scored with 44, and is the fourth leading run-getter of the league.
| Player | Mat | Runs | HS | Ave | SR |
| Sahibzada Farhan | 12 | 447 | 78 | 40.63 | 132.24 |
| Iftikhar Ahmed | 12 | 409 | 58 | 102.25 | 170.41 |
| Sharjeel Khan | 11 | 371 | 101 | 33.72 | 150.81 |
| Ahmed Shehzad | 11 | 344 | 77 | 31.27 | 128.35 |
| Haider Ali | 8 | 317 | 91* | 63.4 | 146.75 |
Most Wickets
Imran Khan took one wicket against Central Punjab to finish the campaign with 16 wickets in 12 games. Arshad Iqbal picked 14 wickets and he is at second. Shaheen Shah Afridi played only six matches and claimed 12 wickets.
| Player | Mat | Wkts | BBI | Econ |
| Imran Khan | 12 | 16 | 4/28 | 8.33 |
| Arshad Iqbal | 12 | 14 | 3/16 | 8.5 |
| Shaheen Shah Afridi | 6 | 12 | 3/25 | 8.58 |
| Rumman Raees | 10 | 12 | 4/33 | 7.05 |
| Wahab Riaz | 12 | 12 | 3/21 | 6.54 |