Most Runs
With 334 runs at a strike rate of 148, Tanmay Agarwal is at the top of the runs chart in Syed Mushtaq Ali Trophy 2021. He is followed by Deepak Hooda (294 at 168), Ajinkya Rahane (286 at 134) and Ashwin Hebbar (279 at 133). Manan Vohra occupies fifth place, with 273 at 131.
| Batters | M | RUNS | AVG | SR |
| Tanmay Agarwal | 7 | 334 | 55.67 | 148.44 |
| Deepak Hooda | 6 | 294 | 73.5 | 168 |
| Ajinkya Rahane | 5 | 286 | 57.2 | 133.64 |
| Ashwin Hebbar | 5 | 279 | 93 | 133.49 |
| Manan Vohra | 5 | 273 | 68.25 | 130.62 |
Most Wickets
With 18 scalps at an economy rate of 8.41, Chama Milind leads the wickets chart. C.V. Stephen and Rishi Dhawan are tied on the second place, with 14 wickets apiece. Akshay Karnewar, Darshan Nalkande and Jaydev Unadkat are joint third, with 13 scalps each.
| Bowlers | M | O | WKTS | AVG | 4W+ |
| Chama V. Milind | 7 | 24.5 | 18 | 11.61 | 2 |
| C.V. Stephen | 5 | 19.5 | 14 | 9.07 | 1 |
| Rishi Dhawan | 6 | 21.5 | 14 | 11.14 | 1 |
| Akshay Karnewar | 8 | 32 | 13 | 10.69 | 1 |
| Darshan Nalkande | 8 | 26 | 13 | 11.77 | 2 |
| Jaydev Unadkat | 6 | 24 | 13 | 11.85 | 1 |