Most runs
With 334 runs at a strike rate of 148, Tanmay Agarwal finished as the leading run-scorer in the 2021/22 Syed Mushtaq Ali Trophy. Deepak Hooda (294 at 168) and Ajinkya Rahane (286 at 134) occupied the next two places, while Ashwin Hebbar finished fourth, with 279 at 133. They are followed by Manan Vohra (273 at 131) and Manish Pandey (272 at 107).
| Batters | Mat | Runs | HS | Ave | SR | 100 | 50 |
| TD Agarwal | 7 | 334 | 97* | 55.66 | 148.44 | 0 | 4 |
| DJ Hooda | 6 | 294 | 75* | 73.5 | 168 | 0 | 4 |
| AM Rahane | 5 | 286 | 75 | 57.2 | 133.64 | 0 | 4 |
| K Ashwin Hebbar | 5 | 279 | 103* | 93 | 133.49 | 1 | 1 |
| M Vohra | 5 | 273 | 106* | 68.25 | 130.62 | 1 | 1 |
| MK Pandey | 9 | 272 | 84 | 30.22 | 107.08 | 0 | 3 |
Most wickets
With 18 scalps at economy rate of 8.2, Chama Milind topped the wickets chart. C.V. Stephen and Rishi Dhawan were next, with 14 wickets apiece. Akshay Karnewar, Darshan Nalkande and Jaydev Unadkat finished joint fourth, with 13 wickets each.
| Bowlers | Mat | Overs | Wkts | BBI | Ave | Econ | SR | 4W+ | 5W+ |
| CV Milind | 7 | 24.5 | 18 | 5/8 | 11.61 | 8.41 | 8.2 | 0 | 2 |
| CV Stephen | 5 | 19.5 | 14 | 4/11 | 8.57 | 6.05 | 8.5 | 1 | 0 |
| R Dhawan | 6 | 21.5 | 14 | 6/23 | 11.14 | 7.14 | 9.3 | 0 | 1 |
| AK Karnewar | 8 | 32 | 13 | 4/5 | 10.69 | 4.34 | 14.7 | 1 | 0 |
| DG Nalkande | 8 | 26 | 13 | 5/9 | 11.76 | 5.88 | 12 | 1 | 1 |
| JD Unadkat | 6 | 24 | 13 | 4/22 | 11.84 | 6.41 | 11 | 1 | 0 |